olistat (alli)

• Olistat (Alli)

  • For adults aged 18 and over
  • BMI greater than or equal to 28 kg/m2
  • to be taken in conjunction with dietary & lifestyle measures
• orlistat referral?

  • Pregnant/ breastfeeding women
  • failure to lose weight after 3 months
  • Chronic malabsorption syndrome
  • Under 18 years old
  • medications: levothyroxine, acarbose, amiodarone, warfarin, anti-epileptics
• Olistat (Alli) is to be taken in conjunction with dietary & lifestyle measures
• Dosage

  • Alli (Orlistat 60mg capsule)
  • 60mg three times daily
  • Immediately before/ during/ up-to 1 hour after each main meal
  • If meal missed/ or contains no fat, then OMIT the dose
  • Maximum of 3 capsules in 24 hours
  • Treatment should not exceed 6 months
• Side effects of orlistat

  • Oily stools
  • Flatulence
• Use additional contraceptive methods if diarrhoea occurs (orlistat reduces availability of oral contraceptives)
• Vitamin supplements should be taken at night (2hrs after orlistat dose) as orlistat impairs absorption of fat-soluble vitamins ("ADEK")=vitamins A, D, E, K
• Healthy life style advice

  • 18-30g fibre daily
  • 2.5L water daily
  • Exercise 30 mins mild/mod intensity x5 times/week