DNA Structure

Cards (9)

  • DNA
    A polynucleotide - made up of many nucleotides bonded together in a long chain
  • DNA molecules
    • Made up of two polynucleotide strands lying side by side, running in opposite directions (antiparallel)
  • Structure of DNA polynucleotide strand
    1. Alternating deoxyribose sugars and phosphate groups bonded together to form the sugar-phosphate backbone
    2. Phosphodiester bonds link the 5-carbon of one deoxyribose sugar to the phosphate group, which is linked to the 3-carbon of the next deoxyribose sugar
  • 3' end and 5' end

    Numbers relating to which carbon on the pentose sugar could be bonded with another nucleotide
  • DNA strands
    • One is 5' to 3' strand, the other is 3' to 5' strand (they run in opposite directions, are antiparallel)
  • Nitrogenous bases
    • Project out from the backbone towards the interior of the double-stranded DNA molecule
  • Hydrogen bonding
    The two antiparallel DNA polynucleotide strands are held together by hydrogen bonds between the nitrogenous bases
  • Complementary base pairing
    • Adenine (A) always pairs with thymine (T) (2 hydrogen bonds)
    • Guanine (G) always pairs with cytosine (C) (3 hydrogen bonds)
  • DNA is described as a double helix (three-dimensional shape formed by the twisting of the DNA molecule)