1. Diastole: Atria and ventricles are relaxed, AV valves are open, deoxygenated blood flows into right atrium
2. Systole: Right atrium contracts, empties into right ventricle, right ventricle contracts, forcing blood out along pulmonary artery, PA valve closes to prevent backflow
3. Blood flows through pulmonary arteries to lungs, picks up O2, CO2 removed, oxygenated blood returns to left atrium
4. Left atrium empties into left ventricle, left ventricle contracts, forcing blood out along aorta, AV valves close to prevent backflow