General causes of illness and disease
Living conditions - crowded houses, contaminated water, rats, mice, fleas
Poor diet - 25% of rural families had enough land to support themselves, child mortality was high and malnutrition was common
Famine - happened regularly in 1069, 1258 and 1437-1439, harshest was 1315-1317 when torrential rain ruined planting and harvesting
War - wounds inflicted by swords and axes became gangrenous