Until the acceptance of germ theory in the 1860s, surgeons did not take any precautions to protect open wounds from infection.
They did not wash their hands before operating, sterilise their equipment or clean the operating table.
Joseph Lister's discovery
1867: He discovered that carbolic spray was very effective in stopping wounds from getting gangrene.
He developed antiseptic surgery by spraying medical instruments, catgut and bandages with a 1-in-20 solution of carbolic acid.
However, the production of better quality glass allowed Joseph Jackson Lister, father of Joseph Lister, in 1826 to make a microscope with 1,000 times magnification.
Joseph Lister laid the foundations for... (after)
Despite the opposition it was soon obvious that Lister's methods were a success.
In 3 years, he reduced the death rate among his patients from 46% to 15%.
Others copied his methods. In the 1880s, appendectomies were being carried out and in 1896, surgeons did the first major cardiac surgery when they repaired a heart damaged by a stab wound.