Plasmodium knowlesi

• Plasmodium knowlesi (Simian Malaria)

  • Fifth human malaria parasite, normally a parasite of a long-tailed macaques (Macaca fascicularis) but humans working nearby forest fringe are at great risk of infection.
• Plasmodium knowlesi (Simian Malaria)

  • Described in humans in the Philippines and Southeast Asia
• Plasmodium knowlesi (Simian Malaria)

  • Microscopically indistinguishable from P. malariae and differentiation is only achieved through PCR assay and molecular characterization.
• Plasmodium knowlesi (Simian Malaria)

  • The early stages mimic P. falciparum, whereas the later stages mimic P. malariae