In planning a study the investigator has the personal responsibility to make careful evaluation of its ethical acceptability
Responsibility for the establishment and maintenance of acceptable ethical practice in research always remains with the individual investigator
Ethical practice requires the investigator to inform the participant of all features of the research that reasonably might be expected to influence willingness to participate
Openness and honesty are essential characteristics of the relationship between investigator and research participant
Ethical research practice requires the investigator to respect the individual's freedom to decline to participate in research or to discontinue participation at any time
Ethically acceptable research begins with the establishment of a clear and fair agreement between the investigator and the research participant
The ethical investigator protects participants from the physical and mental discomfort, harm and danger
After the data are collected, ethical practice requires the investigator to provide the participant with a full clarification of the nature of the study and to remove any misconceptions that may have arisen
Where research procedures may result in undesirable consequences for the participant, the investigator has the responsibility to detect and remove or correct these consequences
Information obtained about the research participant during the course of the investigation is confidential