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PARASITOLOGY
Trematodes (on going)
P. westermani
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P. westermani is otherwise known as
Oriental Lung
Fluke
Mode of transmission - Ingestion of raw/pickled
crayfish
or
freshwater crab
Infective Stage -
Metacercariae
1st Intermediate Host - Snail:
Brotia asperata
2nd Intermediate Host -
Sundathelpusa philippina
Final Host -
Man
Habitat -
Lungs
Coffee-bean shaped body
Paragonimus
westermani
Clinical features resemble Pulmonary tuberculosis
Paragonimiasis
Definitive diagnosis
is based on the detection of characteristic egg on sputum or stool, or less frequently, aspirated from abscess or effusion
Most basic and most readily available diagnostic tool
Disadvantage:
Low
sensitivity (37-88%)
Sputum concentration with
3% NaOH
with repeated examinations up to 3x on different days
Combined with high index of suspicion
Lung parenchyma lesions which may be infiltrative, nodular, or cavitating
Disadvantage: Radiographic findings are non-specific
CHEST RADIOGRAPH
Useful for
Cerebral paragonimiasis
Characteristic finding:
conglomerated
,
multiple ring-enhancing
lesions with a
“grape-cluster”
appearance with surrounding
edema
CT
or
MRI
PRAZIQUANTEL
(
25
mg/kg,
three
times daily, for 2-3 days)
● Drug of choice
● Breastfeeding should be avoided during and
72
hours after treatment
Originally used for
Fasciola hepatica
infection
Cure rate is comparable to
Praziquantel
TRICLABENDAZOLE
BITHIONOL
- Alternative drug to PRAZIQUANTEL and TRICLABENDAZOLE
Most practical way to prevent infection is to avoid ingestion of raw or insufficiently
cooked crabs
and other
crustaceans