P. westermani

Cards (15)

  • P. westermani is otherwise known as Oriental Lung Fluke
  • Mode of transmission - Ingestion of raw/pickled crayfish or freshwater crab
  • Infective Stage - Metacercariae
  • 1st Intermediate Host - Snail: Brotia asperata
    2nd Intermediate Host - Sundathelpusa philippina
  • Final Host - Man
  • Habitat - Lungs
  • Coffee-bean shaped body
    Paragonimus westermani
  • Clinical features resemble Pulmonary tuberculosis
    Paragonimiasis
  • Definitive diagnosis is based on the detection of characteristic egg on sputum or stool, or less frequently, aspirated from abscess or effusion
    Most basic and most readily available diagnostic tool
    • Disadvantage: Low sensitivity (37-88%)
    • Sputum concentration with 3% NaOH with repeated examinations up to 3x on different days
    • Combined with high index of suspicion
    • Lung parenchyma lesions which may be infiltrative, nodular, or cavitating
    • Disadvantage: Radiographic findings are non-specific
    CHEST RADIOGRAPH
    • Useful for Cerebral paragonimiasis
    • Characteristic finding: conglomerated, multiple ring-enhancing lesions with a “grape-cluster” appearance with surrounding edema
    CT or MRI
  • PRAZIQUANTEL (25 mg/kg, three times daily, for 2-3 days)
    ● Drug of choice
    ● Breastfeeding should be avoided during and 72 hours after treatment
    • Originally used for Fasciola hepatica infection
    • Cure rate is comparable to Praziquantel
    TRICLABENDAZOLE
  • BITHIONOL - Alternative drug to PRAZIQUANTEL and TRICLABENDAZOLE
  • Most practical way to prevent infection is to avoid ingestion of raw or insufficiently cooked crabs and other crustaceans