L45 Parathyroid and calcium homeostasis

• describe parathyroid gland

  -small in size

  -posterior to thyroid gland
• describe the histology of parathyroid

  -arranged in thick

  -large numbers of chief cells that secrete parathyroid
• state 3 target organs for parathyroid hormone

  -skeleton

  -kidneys

  -intestine
• what is parathyroid hormone ?

  -small protein

  -control calcium homeostasis

  -triggered by falling blood Ca levels

  -inhibited by hypercalcemia
• calcium metabolism control by 3 hormones. name all of it

  -parathyroid hormone

  -vitamin D

  -calcitonin
• functions of parathyroid hormone

  -bone resorbtion

  -distal tubule reabsorption

  -absorption Ca2+ ion
• how parathyroid help in Ca2+ regulation in bone, kidneys and intestines

  bone: efflux of calcium

  kidneys: decrease loss of Ca2+

  intestine: enhances absorption
• abnormalities of parathyroid hormone function

  hypocalcemic tetany
• role of Bovine Parathyroid Calcium Receptor (BOPCAR)

  -regulating parathyroid hormone (PTH) secretion based on calcium concentration.