Microorganisms exist everywhere: in water, in soil, and on body surfaces such as the skin, intestinal tract, and other areas open to the outside (e.g., mouth, upper respiratory tract, vagina, and lower urinary tract)
Communicable Disease
An illness caused by an infectious agent or its toxins that occurs through the direct or indirect transmission of the infectious agent or its products from an infected individual or via an animal, vector or the inanimate environment to a susceptible animal or human host
Virulence
Severity or harmfulness of a disease
Infection
Implantation and successful replication of an organism in the tissue of the host resulting in signs and symptoms
Infectious Agent
Microorganism or Etiologic Agent
Types of Microorganisms
Bacteria
Fungi
Parasites
Virus
Pathogenicity
Ability of an organism to produce a disease
Pathogen
Microorganism that causes disease
A true pathogen is an infectious agent that causes disease in virtually any susceptible host. Opportunistic pathogens are potentially infectious agents that rarely cause disease in individuals with healthy immune systems
Asepsis
Freedom from disease-causing microorganisms
Medical Asepsis
"Clean Technique" - practices intended to confine / reduce microorganism
Surgical Asepsis
"Sterile Technique" - practices that keep an area or object FREE of ALL microorganisms
Sepsis
The condition in which acute organ dysfunction occurs secondary to infection
Bacteremia
When a culture of the individual's blood reveals microorganisms
Septicemia
When bacteremia results in systemic infection
Major Categories of Microorganisms
Bacteria
Virus
Fungi
Parasites
Colonization
The process by which strains of microorganisms become resident flora. In this state, the microorganisms may grow and multiply but do not cause disease
Local infection
Limited to the specific part of the body where the microorganisms remain
Systemic infection
The spread of infection to different parts of the body
Acute infections
Generally appear suddenly or last a short time
Chronic infection
May occur slowly, over a very long period, and may last months or years
Healthcare-Associated Infections
CLABSI (Central IV Line-Associated Bloodstream Infection)
CAUSES: Improper tubing and site care technique, Inadequate hand hygiene
CAUTI
CAUSES: Improper catheterization technique, Contamination of closed drainage system, Inadequate hand hygiene
SSI
CAUSES: Improper dressing change, Inadequate hand hygiene
VAP
CAUSES: Improper suctioning, Inadequate hand hygiene
2019 The Joint Commission National Patient Safety Goals - Goal 7: Reduce the Risk of Healthcare-Associated Infections
Goal 7 Requirements
Comply with either the current CDC hand hygiene guidelines or the current WHO hand hygiene guidelines
Implement evidence-based practices to prevent HAIs due to: Multidrug-resistant organisms, CLABSI, CAUTI, SSI
5 Moments of Handwashing
For routine client care, vigorous hand washing under a stream of water for 15 to 20 seconds using soap at the beginning of the nurse's shift, when hands are visibly soiled, and after using the toilet is recommended (WHO, 2009). After the initial soap and water hand washing, the CDC recommends the use of alcohol-based antiseptic hand rubs (rinses, gels, or foams) before and after each direct client contact
Iatrogenic infections
The direct result of diagnostic or therapeutic procedures. Ex: Bacteremia that results from an intravascular infusion line
The hands of healthcare personnel are a common vehicle for the spread of microorganisms
Factors contributing to nosocomial infections
ETIOLOGIC AGENT
RESERVOIR
PORTAL OF EXIT FROM RESERVOIR
METHOD OF TRANSMISSION
PORTAL OF ENTRY TO THE SUSCEPTIBLE HOST
SUSCEPTIBLE HOST
ETIOLOGIC AGENT
Any microbe capable of producing disease (i.e. bacteria, virus, fungi, parasite)
RESERVOIR
Where organisms survives and multiplies (people, animals, food, water, soil). A carrier is a human or animal reservoir.
PORTAL OF EXIT FROM RESERVOIR
Microorganism: M. Tuberculosis, Reservoir: Respiratory Tract, Portal of exit: Nose or mouth by sneezing, coughing
Methods of Transmission
Direct Transmission
Indirect Transmission
Droplet Transmission
Airborne Transmission
Vehicle-born Transmission
Vector-born Transmission
Direct Transmission
From individual to individual through: touching, biting, kissing, sexual intercourse