Candidate Genes, OCD is polygenic, Different types of OCD, Diathesis-stress model
Role of serotonin, The Orbito-frontal circuit
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The genes associated with OCD are likely to affect the levels of key neurotransmitters as well as structures of the brain these are: NEURAL EXPLANATIONS
Candidate Genes & OCD
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OCD is Polygenic
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Different types of OCD
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Diathesis-Stress Model
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Lewis (1936)
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Neural Explanations
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Neurotransmitters responsible for
Relaying information from one neuron to the other across a synapse
What is serotonin?
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Role of Serotonin in OCD & low levels of serotonin means?
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Role of serotonin in OCD = This explanation of OCD came out due to the success of early antidepressants (Clomipramine) in relieving symptoms of OCD. Clomipramine increases the amount of serotonin available in the synapse.
The Orbito-frontal circuit?
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In healthy people & the orbito-frontal circuit?
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People with OCD & the orbito-frontal circuit?
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The brain is made up of neuronal pathways (or brain circuits)
What is the OFC linked with?
The OFC is linked with thoughts, decisions making & planning
OFC is a ___? And consists of? located where?
The OFC is a neuronal pathway that connects the Orbitofrontal cortex (situated close to eyes) with other parts of the brain.
This neuronal pathway consists of both an excitatory pathway and an inhibitory pathway.
Parahippocampal Gyrus Dysfunctional & OCD
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Genes associated with OCD are likely to affect the levels of key neurotransmitters as well as structures of the brain. These are NEURAL EXPLANATIONS.
What to most drugs for treating OCD aim to do?
OCD is associated with low levels of serotonin and therefore drugs work to increase levels of serotonin in the brain.