12. Developmental Renal Diseases - Sakrani

• Cystic Kidney Diseases

  • epithelium-lined cavities filled with fluid that develops from defect in structure + function of tubular epithelial cells
• Acquired: cystic kidney disease that develops in patients with existing ESRD
• Acquired cystic kidney disease (ACKD) risk factors

  • CKD
  • end stage renal disease
  • dialysis pts
• Autosomal recessive form of polycystic kidney disease (ARPKD) - affects kids
• ARPKD - mutation in a single gene - PKHD1