Stimulus: Excessive water intake dilutes blood solutes. Excessive antidiuretic hormone (ADH) secretion. Heart, liver or Kidney Disease
Osmoreceptors in the hypothalamus detect low blood osmolarity
Hypothalamus: signals the posterior pituitary to reduce or stop releasing ADH
Kidneys: without ADH, the collecting ducts in the kidneys become less permeable to water (kidneys will not absorb water)
Response: more water is excreted in the urine, reducing blood volumes and slightly increasing osmolarity. Urine becomes less concentrated
Feedback: As blood osmolarity rises back to normal levels, ADH suppression decreases, maintaining balance. Ensures proper osmotic balance and prevents excessive dilution of bodily fluids