COOPERATIVE BINDING

Cards (3)

  • WHAT IS THE COOPERATIVE NATURE OF O2 BINDING TO HAEMOGLOBIN DUE TO?
    haemoglobin changing shape when the first oxygen molecule binds
  • WHAT DOES THE FIRST OXYGEN MOLECULE BINDING TO HAEMOGLOBIN CAUSE?
    easier for further oxygen molecules to bind
  • HOW DOES COOPERATIVE BINDING WORK?
    • first molecule of oxygen binds to haemoglobin
    • causes conformational change of tertiary structure
    • easier for next two oxygen molecules to bind
    • due to high affinity for oxygen
    • haemoglobin is more saturated
    • lower chance of oxygen colliding with final haem group
    • harder for final oxygen molecule to bind