Globular vs Fibrous proteins

• Globular proteins:

  • Highly folded, so its a compact, spherical molecule
  • Not very stable, tertiary structure is easily disrupted
  • Important when precise shapes are needed for molecular interactions e.g. enzymes
• Fibrous proteins:

  • Polypeptide chains do not fold
  • Remain as straight chains, often with several parallel chains cross-linked
  • Sometimes form sheets
  • Insoluble
  • Very stable + 💪 
  • Important structural molecules e.g. hair
• Haemoglobin vs Collagen