the view that both nature and nurture work together to shape human behaviour
the diathesis stress model:
highlights the significance of environmental factors and biological factors
explains that individuals will develop Sz if they have a biological predisposition and if they are exposed to stressful situations
diathesis
the findings from identical twins supports the idea of a genetic component in terms of vulnerability
an identical twin of a person with Sz is at greater risk of developing Sz than a sibling or Dz twin
however concordance rates are only around 48%
this indicates that environmental factors must also play a role in determining whether a biological vulnerability for Sz actually develops into the disorder
stress
stressful life events may be able to trigger Sz, can be a variety of forms like childhood trauma or everyday stressors from a highly urbanised life
research suggests that a high level of urbanisation is associated with an increased risk of developing a range of different psychoses
Vassos et al: meta-analysis found that the risk of Sz in the most urban environments were estimated to be 2.37 times higher than in the most rural areas
relationship: urban stress + Sz is conditional on some other factor, a pre-existing genetic risk for the disorder as well as family dysfunction
high and low vulnerability
Tienari et al (2004)
hypothesis: genetic factors moderate susceptibility to environmental risks associated with adoptive family functioning
sample: mothers with Sz who have had children adopted away - 145 adopted away offspring (high risk group)
matched with 158 adoptees without genetic risk (low risk group)
procedure: both groups of adoptees were independently assessed after 12 years and then followed up 21 year later
psychiatrists family functioning using OPAS which measures families on various aspects such as conflict, lack of empathy and insecurity
tienari
findings: of the 303 adoptees, 14 developed Sz - 11 were from the high risk group and 3 low risk group, being reared in a healthy adoptive family with low OPAS rating seemed to have a protective effect even those at high genetic risk
high genetic risk + low OPAS were significantly less likely to have developed Sz
conclusion: in adoptees at high genetic risk of Sz adoptive family stress was a significant predictor of the development of Sz
when assessed, only assessed at one point in time which fails to reflect developmental changes in family functioning over time
evaluation:
diathesis may not be exclusively genetic
it emphasises vulnerability in terms of genetic influences alone but this can increase the risk of brain damage caused by environmental factors
Verdoux et al (1998) the risk of developing Sz from complicatios at birth is four times greater
importance of the approach: support for the usefulness of the combination of drugs and CBT, patients showed lower symptoms and the approach is more cost-effective
interactive treatment (drugs and CBT) are needed for effective treatment
evaluation:
too simplistic/reductionist
the idea that a single gene combined with a certain parenting style cause the Sz is too simplistic
multiple genes have been found to increase the risk of developing the illness indicating that there is no single- schizogene
not limited to just parenting style and family dynamics
a holistic and interactionist approach to understanding the onset of Sz is needed, idiographic research should be conducted and personalised triggers found
Cannabis is a stressor and increases the risk of Sz by seven times