Neural and genetic explanations for OCD AO3

• What percentage of concordance in OCD was found in MZ twins according to NESTADT?

  68%
• What percentage of concordance in OCD was found in DZ twins according to NESTADT?

  31%
• What does the high concordance rate in MZ twins suggest about the role of genes in OCD?

  It suggests that shared genes play a significant role in the development of OCD.
• What is the diathesis-stress model in relation to OCD?

  It suggests that a genetic predisposition is coupled with an environmental trigger to develop a disorder.
• Who found that over 50% of OCD patients had experienced a traumatic event?


  CROMER
• How does the diathesis-stress model explain the development of OCD?

  It explains that genetic predisposition combined with environmental triggers leads to the disorder.
• What is a limitation of the neural explanations for OCD regarding cause and effect?

  Drugs that affect serotonin may alleviate symptoms, but this does not confirm serotonin imbalance as the initial cause.
• What is the improvement rate for SSRIs in treating OCD symptoms?

  50%
• What did CAVEDINI's research suggest about decision-making systems in OCD patients?


  It suggested that decision-making systems function abnormally in individuals with OCD.
• Why can't neurophysiological factors be considered the sole cause of OCD?


  Because these factors are not consistently involved in all individuals with OCD.
• What did Luo's structural MRI studies reveal about individuals with OCD in China?

  They found that individuals with OCD had a smaller volume of white matter in the left parahippocampal gyrus compared to those without OCD.
• Why is Luo's study significant in understanding OCD?

  It provides empirical evidence suggesting that OCD has a neural origin.
• What does the inclusion of patients who responded to treatment and those who didn't in Luo's study provide?

  It gives a broader understanding of the causes of OCD in different groups of people.