Hydatidiform Mole

• Hydatidiform Mole

  Is also known as Gestational Trophoblastic Disease
• Hydatidiform Mole

  Hallmark sign: passage of clear fluid-filled grapesized vesicles
• Hydatidiform Mole

  Clinical Manifestations:

  • high HCG
  • vaginal bleeding
  • rapid increase in fundic height
  • absent FHT
  • ultrasound: snowstorm pattern
• Hydatidiform Mole

  Management:

  • no pregnancy within 1 year to allow HCG levels to decrease
  • D&C or vacuum aspiration
  • Drug: Methotrexate - an anti-neoplastic agent that kills rapidly dividing cells (may cause abortion in normal pregnancy)

  Recurrent H-mole predisposes patient to uterine cancer.