If epidural contraindicated or declined - PCA with fentanyl/remifentanil, IM or IV morphine or diamorphine, pethidine
Entonox:
Inhaled nitrous oxide
50% oxygen and 50% nitrous oxide
Short half life - peat effect in 20-30 seconds
Weak anaesthetic at high concentration
Analgesic + anxiolytic at low concentration
Increases endogenous endorphin release
Can make women feel lightheaded and dizzy
Possible nausea and vomiting
Pethidine and diamorphine:
Usually given IM
Opioids
May cause nausea and drowsiness in the mother
Can cause respiratory depression in the neonate if given too close to birth
Epidural:
Local anaesthetic and opioid into epidural space in the lower back
Anaesthetic options - levobupivacaine or bupivacaine, usually mixed with fentanyl
Need catheter inserting
Reversible loss of sensory and motor function
Adverse effects:
Headache (post dural puncture headache)
Hypotension
Significant motor weakness in the legs
Nerve damage
Prolonged second stage
Increased probability of instrumental delivery
Length of first stage:
First labour - average 8 hours (unlikely over 18 hours)
Second and subsequent labour - average 5 hours (unlikely over 12 hours)
Vaginal assessment:
Vaginal examination offered every 4 hours during first stage
To assess rate of cervical dilatation
Want 1cm/hour
Failure to progress:
Less than 2cm of cervical dilatation in 4 hours, or slowing of progress in a multiparous woman
Crossing the alert line on a partogram is an indication for an amniotomy (artificially rupturing membranes) and repeat examination in 2 hours - if membranes not already ruptured
Crossing the action line means care needs to be escalated to obstetric led care
Oxytocin is used first line to stimulate uterine contracts during labour
Other options - instrumental delivery and caesarean section
Oxytocin:
Recombinant hormone
Produced by hypothalamus and stored in posterior pituitary - released in pulses during childbirth
Oxytocin receptors in myometrium increase during pregnancy - increased strength and frequency of uterine contractions
Oxytocin regulated by positive feedback - head of foetus pushing on cervix signals release
Used first line to stimulate uterine contracts during labour - started at a low rare and titrated up
Aim for 4-5 contractions per 10 minutes
Too many contractions can result in foetal compromise - no opportunity to recover