Cell Cycle

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EJAW

Cards (21)

  • Cell Cycle

    The series of events that take place in a cell leading to its division and duplication (replication).
  • Interphase

    Preparation for Division
  • Mitotic Phase

    Division of the Cell.
  • Interphase: G1 phase

    Cell growth, preparation for DNA replication.
  • Interphase: S Phase Synthesis

    DNA replication occurs.
  • Interphase: G2 phase (second gap)

    Cell continues to grow and prepares for mitosis.
  • Mitosis

    Division of the nucleus
  • Cytokinesis

    Division of the cytoplasm
  • Mitotic Phase: G1 Phase
    G1 Checkpoint:
    • Cell checks for DNA damage.
    • Determines if the environment is favorable for division.
  • Mitotic Phase: S phase
    Key events:
    • DNA is Replicated.
    • Each chromosome consist of two sister chromatids.

    Importance:
    • Ensures that the daughter cells will have the exact same genetic material as the parent cell.
  • Mitotic Phase: G2 Phase
    Key events:
    • Cell continues to grow.
    • Prepares for mitosis by producing proteins needed for chromosomes manipulation.
    Checkpoint:
    • Ensures all DNA has been replicated properly.
    • Checks for DNA damage before the cell enters mitosis.
  • Mitotic Phase: M phase

    Ensures:
    • Chromosomes are properly attached to the spindle fibers.
    • Prevents chromosome mis segregation, ensuring each number of chromosomes.
  • Metaphase

    Chromosomes line up in the middles.
  • Anaphase

    Sister chromatids are pulled apart.
  • Telophase

    Nuclei form around the chromatids.
  • Cytokinesis

    Cytoplasm divides, resulting in two daughter cells.
  • G1 checkpoint

    Restriction point where the cell commits to division.
  • G2 checkpoint

    Checks DNA for damage and ensures all DNA is replicated o spindle fibers before mitosis
  • M checkpoint 

    Ensures proper attachment of chromosomes to spindle fibers before anaphase.
  • Why control point matters?
    • Prevent errors in DNA replication.
    • Ensures equal distribution of chromosomes to daughter cell.
    • Avoids uncontrolled cell division
  • Uncontrolled cell division

    Leads to cancer