Fibrocartilage Callus Formation
○ 48 hours after the fracture, stem cells on the endosteum of the bone will undergo differentiation to be chondrocytes.
○ These cartilage cells will secrete a fibrocartilaginous matrix between the two ends of the broken bone.
○ Gradually, this newly-forming matrix reunites the ends of the broken bone into an internal callus.
○ Periosteal chondrocytes work together with osteoblasts to create an external callus.
○ Both external and internal calluses stabilize the fracture.