Cancer Staging and Grading

• General Cancer Staging

  Stage 0 - stayed in the place where it began and has not spread neighboring tissues
• General Cancer Staging

  Stage 0 - carcinoma in situ
• General Cancer Staging

  Stage I - tumor limited to the tissue of origin
• General Cancer Staging

  Stage II - limited local spread
• General Cancer Staging

  Stage III - extensive local and regional spread
• General Cancer Staging

  Stage IV - distant metastasis
• General Cancer Staging

  Stage IV - Cancer has spread to other organs or areas of your body
• TNM Staging: Tumor

  TX - Unable to evaluate the primary tumor
• TNM Staging: Tumor

  T0 - No evidence of primary tumor
• TNM Staging: Tumor

  Tis - Tumor in situ
• TNM Staging: Tumor

  T1 - 2cm or less
• TNM Staging: Tumor

  T2 - 3 to 5 cm
• TNM Staging: Tumor

  T3 - >6 cm
• TNM Staging: Tumor

  T4 - direct extension to chest wall or skin
• TNM Staging: Node

  NX - Unable to evaluate regional lymph nodes
• TNM Staging: Node

  N0 - No evidence of regional node involvement
• TNM Staging: Node

  N1 - <4 regional nodes involed
• TNM Staging: Node

  N2 - >4 regional nodes involed
• TNM Staging: Node

  N3 - Distant nodes involved
• TNM Staging: Metastasis

  MX - Unable to evaluate distant metastasis
• TNM Staging: Metastasis

  M0 - No evidence of distant metastasis
• TNM Staging: Metastasis

  M1 - Presence of distant metastasis
• Cancer Grading

  GX - Grade cannot be determined
• Cancer Grading

  G1 - Tumor cells are well differentiated
• Cancer Grading

  G2 - Tumor cells are moderately differentiated
• Cancer Grading

  G3 - Tumor cells are poorly differentiated but the tissue of origin can be established
• Cancer Grading

  G4 - Tumor cells are poorly differentiated, and determination of the tissue of origin is difficult