MECHANISMS

• CONDITIONS FOR REACTION OF ACYL CHLORIDE AND WATER?

  cold water
• ANOTHER NAME FOR THE REACTION OF ACYL CHLORIDE AND WATER?

  hydrolysis
• WHAT IS PRODUCED WHEN ETHANOYL CHLORIDE AND WATER REACT?

  ethanoic acid and HCl
• CONDITIONS FOR REACTION OF ACYL CHLORIDE AND ALCOHOL?

  reflux in dry (anhydrous) conditions
• WHAT IS PRODUCED WHEN ETHANOYL CHLORIDE AND ETHANOL REACT?

  ethyl ethanoate and HCl
• CONDITIONS FOR REACTION OF ACYL CHLORIDE AND AMMONIA?

  low temperature, excess ammonia
• WHAT TYPE OF REACTION IS THE REACTION BETWEEN ACYL CHLORIDE AND AMMONIA?

  vigorous
• WHAT IS PRODUCED WHEN AMMONIA REACTS WITH ETHANOYL CHLORIDE?

  2NH3: ethanamide and NH4Cl (ammonium chloride)

  OR

  NH3: ethanamide and HCl
• CONDITIONS FOR REACTION OF ACYL CHLORIDE AND PRIMARY AMINE?

  anhydrous
• WHAT IS PRODUCED WHEN ETHANOYL CHLORIDE AND METHYLAMINE REACT?

  N-methyethanamide and HCl
• CONDITIONS FOR ACID ANHYRDIDE AND WATER?

  warm
• CONDITIONS FOR ACID ANHYRDIDE AND AMMONIA?

  warm, reacts slowly
• CONDITIONS FOR ACID ANHYRDIDE AND ALCOHOL?

  gentle heating
• CONDITIONS FOR ACID ANHYRDIDE AND PRIMARY AMINE?

  gentle heating
• WHAT IS PRODUCED WHEN ACID ANHYDRIDE AND WHAT REACT?

  WATER: carboxylic acid + carboxylic acid

  AMMONIA: amide + carboxylic acid

  ALCOHOL: ester + carboxylic acid

  PRIMARY AMINE: N-substituted amine + carboxylic acid
• WHAT IS PRODUCED WHEN ACYL CHLORIDE AND WHAT REACT?

  WATER: carboxylic acid + hydrochloric acid

  ALCOHOL: ester + hydrochloric acid

  AMMONIA: amide + hydrochloric acid

  PRIMARY AMINE: N-substituted amide + hydrochloric acid
• CONDITIONS FOR ACYL CHLORIDE AND WHAT?

  WATER: cold water

  ALCOHOL: reflux in dry (anhydrous) conditions

  AMMONIA: low temperature, excess ammonia

  PRIMARY AMINE: anhydrous
• CONDITIONS FOR ACID ANHYDRIDE AND WHAT?

  WATER: warm

  ALCOHOL: warm

  AMMONIA: gentle heating

  PRIMARY AMINE: gentle heating