Prokaryotes: single celled organisms (unicellular) that lack membrane-bound organelles, do not have a nucleus, are significantly smaller than eukaryotes and have a single, circular chromosome made of DNA -- grouped within two domains, Bacteria and Archaea
Eukaryotes: can be unicellular or multicellular, have internal membrane-bound organelles, has nucleus, relatively larger, have linear chromosomes -- found in Kingdown Protista, Fungi, Plantae, Animalia