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Schizophrenia
Biological Explanations of Schizophrenia
neural correlates
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Cards (13)
What are neural correlates?
Measurements of the
structure
/function of the brain that correlate with an
experience.
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What types of symptoms have neural correlates?
Both
positive
and
negative
symptoms have neural correlates.
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What does avolition involve?
Avolition involves the loss of
motivation
.
The
ventral
striatum
is believed to be involved in the anticipation of reward which links to motivation. Abnormalities of this is involved in the development of avolition
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How are abnormalities of the
ventral striatum
related to
avolition
?
Abnormalities of the ventral striatum are thought to be involved in the development of avolition.
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What was the finding of
Juckel
(
2006
) regarding activity levels in the
ventral striatum
?
They found lower levels of activity compared to the control group.
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What correlation did
Juckel
(2006) find between activity levels in the
ventral striatum
and
negative symptoms
?
They found a negative correlation between activity levels and severity of overall negative symptoms.
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What are the neural correlates of positive symptoms according to
Allen
(2007)?
Lower levels of activity in the
superior temporal gyrus
and
anterior cingulate gyrus
.
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What task did
Allen
(
2007
) use to study patients experiencing
auditory hallucinations
?
They scanned the brains while patients identified their own speech from others off a recording.
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What was a significant finding regarding errors made by the hallucination group in
Allen
(
2007
)?
This group made more errors compared to the control group.
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What structural change is observed in the brains of some
patients
with
schizophrenia
?
Patients have less
brain tissue
.
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What enlargement has been observed in the
cerebral ventricles
of some
schizophrenia
patients?
Enlargement of the cerebral ventricles by
15%
larger.
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What did
post-mortem studies
reveal about
brain cells
in
schizophrenia
patients?
Changes in the amount and distribution of brain cells in some people with schizophrenia.
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What are the strengths and weaknesses of the evidence supporting
neural correlates
in
schizophrenia
?
Strengths:
Evidence to support neural correlates
Scientific testing of brain areas using scans
Weaknesses:
Uncertainty about
cause and effect
No single area of the brain seems to cause schizophrenia
Evidence is
inconsistent
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