"Call up her father, rouse him, make after him, poison his delight, plague him with flies."
- Disease imagery; disease is dangerous and deadly, anticipating Iago's plans as being deadly ones. Ironic, Iago's scheming will lead to Othello's, Desdemona's and Emilia's death.
- Despite it being evident that disease is deadly, in repeatedly using language which is used to describe a disease - a "plague", Iago implies the extent of his plans and how dangerous they are. They are so dangerous that they can only be escaped by death.
- Ironic - "plague him with flies"; he preys on the weaknesses of the characters and manipulates them to his own benefit, to the extent that they are plagued by Iago. Iago takes an unnatural position, giving himself power over people's lives and controlling their lives. There is no treatment for the characters that fall victim to him as they are plagued by him and cannot get rid of the plague unless Iago no longer exists. As long as Iago exists, his evilness (his plague) will extend to all characters, making them a victim of him,
- "Poison" -> Witchcraft; in Jacobean times, it was believed that black people were the ones who were associated with witches and therefore, were to be feared. However, it is very ironic that it is not Othello who takes on a witch-like position. It is Iago.
- Brabantio as a victim of Iago. So far, both Roderigo and Brabantio are Iago's targets. As the play progresses, Iago acquires more and more targets which shows how dangerous his plan is, but also how smart he is as a character. He is an opportunist, preying on the weaknesses of the characters.