Descending Limb

    Cards (2)

    • Filtrate enters PCT isotonic to blood plasma, osmosis and facilitated diffusion occur, causing filtrate to become highly solute concentrated and hypertonic to blood plasma
    • Wall cell’s plasma membranes are water permeable (have aquaporins), water diffuses out of filtrate by osmosis and enters medulla, and are slightly permeable to Na+ and Cl- ions, slowly diffuse from medulla to filtrate by facilitated diffusion
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