Bones 6

• What is the most common type of bone tumor in dogs

  Osteosarcoma
• Where do osteosarcomas commonly metastasize to 


  The lungs
• Predilection sites for osteosarcomas in dogs 


  Distal femur

  Proximal humerus

  Distal radius

  Proximal tibia

  All these originate in the metapyses of all these sites
• How do most osteosarcomas appare in radiology 


  Most are lytic

  Some can be seen with new bone formation
• What is common sign of plasma cell myeloma 


  Elevated calcium levels due to bone lysis
• How does plasma cell myeloma occur 


  Cells produce immunoglobullin of Ig fragment ,monoclonal peak on serum leading to electrophoresis which is secreted into urine causing bence Jones proteinuria
• Plasma cell myeloma pathological findings 


  Lytic lesions especially in vertebral bones and ribs

  Hypercalcemia

  Hyperproteinaemia

  Bence Jones proteinuria

  Al amyloidosis
• Which condition involves multiple radiodense nodules in a joint

  Synovial chondromatosis
• What are the malignant tumors of joints 


  Synovial sarcoma - found in dogs cat and cattle in major weight bearing joints of limbs

  Histocytic sarcoma- commonly found in Rottweilers ,bull mastiff and Retriever

  They are derived from dendritic cells un synovium or skin