Research in this field is correlational only
This means that cause-effect cannot be established
This is a limitation as it leaves too many unanswered questions e.g.
why does grey matter build up in specific brain regions?
what other possible factors could account for the grey matter?
how can cause-effect be found when the sample sizes used in the research are generally so small (e.g. Maguire only used 16 taxi driver participants)?