The tricyclic clomipramine (brand name Anafranil) was the first antidepressant to be used for OCD and nowadays is primarily used to treat OCD rather than depression.
Tricyclics block the transporter mechanisms that re-absorb serotonin and noradrenaline into the pre-synaptic cell after it has fired🔥
As a result, more of these neurotransmitters are left in the synapse, prolonging their activity and easing the transmission of the next impulse.
