HIV

• HIV replication 


  virus binds to CD4 receptor on T helper cell

  virus envelope fuses with T helper cell membrane

  virus RNA and enzymes enter cell

  reverse transcriptase forms viral DNA from viral RNA

  viral DNA becomes double stranded

  integrase binds viral DNA to host DNA

  virus proteins are transcribed and translated

  virus buds out of T helper cell destroying it
• factors that cause AIDs 


  health of person

  lifestyle

  nutrition

  availability of treatment
• acute phase 


  HIV antigens appear in blood after 3-12 weeks

  may experience fever, sweats, headache, sore throat or no symptoms

  rapid replication of virus

  loss of T helper cells

  T killer cells destroy infected T helper cells
• chronic phase 


  can still have no symptoms or increasing symptoms

  dormant diseases can reactivate
• an example of a dormant disease is TB
• disease phase 


  immune system is venerable

  normal infections can be lethal
• reverse transcriptase 


  enzyme found in HIV

  turns viral RNA into viral DNA
• integrase 


  enzyme

  integrates viral DNA and host DNA