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Biology
5 - Cells and immune system
HIV and viruses
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Created by
Grace Findlay
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Cards (47)
What does HIV stand for?
Human Immunodeficiency
Virus
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What condition does HIV cause?
AIDS
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What is the main effect of HIV on the immune system?
It
weakens
the
immune system
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What happens to helper T cells when infected by HIV?
They are killed by the virus
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What is the typical time frame for HIV to develop into AIDS without treatment?
About
10 years
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What is the latency period in HIV infection?
Time
with
few
or
no
symptoms
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What are the initial symptoms of AIDS?
Minor infections of
mucous membranes
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What serious infections can develop during late-stage AIDS?
Toxoplasmosis
and candidiasis
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How does the number of immune system cells change as AIDS progresses?
It decreases
significantly
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What factors affect the progression of HIV to AIDS?
Healthcare access, HIV
strain
,
age
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What is the structure of HIV described as?
Complex
structure
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What are the stages of HIV replication?
Attachment to host cell
Capsid release and uncoating
Reverse transcription to DNA
Insertion into host DNA
Viral protein production
Assembly of new viruses
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Why can't antibiotics be used against viruses?
Viruses lack their own
enzymes
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What do antiviral drugs target in viruses?
Specific
enzymes
used for
replication
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What is an example of a drug used to treat HIV?
Reverse transcriptase inhibitors
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How can HIV be transmitted?
Unprotected
sex
, sharing needles
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How can the risk of an HIV-positive mother transmitting the virus to her baby be reduced?
By taking
antiviral
drugs during pregnancy
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What is the role of helper T cells in the immune response?
They are the main defense against
infection
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What happens to the viral load as HIV progresses?
It
can
vary
greatly
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What is the effect of the national drug program on AIDS?
Delays
onset
by over
100
days
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What happens to the immune system as helper T cells decrease?
It
becomes
weaker
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What type of infections do AIDS patients become susceptible to?
Opportunistic infections
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What is the main cause of death in AIDS patients?
Serious
infections
, not HIV itself
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How does HIV evade the immune response?
By varying the structure of
attachment proteins
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What is the role of reverse transcriptase in HIV replication?
It makes DNA from
RNA
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What is the significance of the capsid in HIV?
It protects the
viral
genetic
material
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What is the function of host cell enzymes in HIV replication?
They
make
viral proteins
from
DNA
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What is the outcome of HIV infection on the body?
Increased susceptibility to
infections
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What is the relationship between viral load and T cell count?
As
viral
load
increases
,
T
cells
drop
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What is the role of macrophages in HIV infection?
They are affected but less targeted
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What is the impact of age on HIV progression?
It can affect
survival time
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What is the significance of the immune response to HIV?
It cannot completely destroy the virus
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What is the effect of HAART on HIV progression?
It slows down progression to
AIDS
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What is the role of B cells in HIV infection?
They are
less
important
targets
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What is the relationship between HIV and opportunistic pathogens?
HIV makes the body
vulnerable
to them
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What is the role of the immune system in fighting HIV?
It
attempts
to
respond
but
fails
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What is the significance of the viral load in HIV infection?
It
indicates
the
severity
of
infection
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What is the impact of healthcare access on HIV progression?
It can improve
survival rates
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What is the effect of sharing needles on HIV transmission?
It increases the risk of transmission
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What is the role of the immune response in HIV infection?
It tries to fight the
virus
but is ineffective
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