Gottesman's large-scale family study (1991) confirmed risk of schizophrenia increases in line wth genetic simularity, however family members tend to be exposed to the same enviroment causing a correlation between genetics and enviroment.
Candiategenes
Multiple gees are involved in the diagnosis of schizophrenia (it is polygenic)
Ripkeet al (2014) conclded that schizophrenia is aetiologicallyheterogeneous (combination of factors e.g. genetic variation
Mutation in schizophrenia
Can be caused by mutated parental DNA (radiation, poison or infection)
