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The Medicine
Calculations
Equations & Graphs
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Cards (56)
What is the act or process of equating?
Equating
or
being
equated
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What is the first definition of an equation?
The state of being
equal
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What does a mathematical equation assert?
It asserts the equality of two
expressions
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How is a mathematical equation typically written?
As a
linear
array with an
equal sign
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What does a chemical equation represent?
A chemical reaction with
reactants
and
products
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What is the term for the adjective form of equation?
Equational
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What is the adverb form of equation?
Equationally
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What are some applications of equations in pharmacy?
Used for
conversions
,
density
, and dilutions
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What are the key uses of equations in pharmacy?
Rearranging
Deriving
units
Noting constants and variables
Simplifying complex equations
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How do you calculate density?
Density =
mass
/
volume
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How can you rearrange the density equation to find mass?
Mass = density x
volume
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How can you rearrange the density equation to find volume?
Volume =
mass/density
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What are the hints for dealing with equations?
D =
Diffusion coefficient
R =
Gas constant
T = Absolute temperature
h =
Viscosity
r = Radius of the diffusing particle
N =
Avogadro’s number
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What is the Stokes-Einstein equation for diffusion coefficient?
D =
R
T
6
π
h
r
N
\frac{RT}{6 \pi h r N}
6
πh
r
N
RT
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What are the SI units of the diffusion coefficient D?
kg m<sup>2</sup> s<sup>-2</sup> mol<sup>-1</sup> K<sup>-1</sup>
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How do you compare diffusion coefficients of two drugs?
Using the
ratio
of their diffusion coefficients
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What is the Henderson-Hasselbalch equation?
pH
=
pKa
+
log
{[
salt
]/[
acid
]}
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How do you calculate the amount of sodium acetate needed for a buffer?
Using the
Henderson-Hasselbalch equation
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What is the pKa of acetic acid?
4.76
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How do you find the concentration of salt needed for a buffer?
By solving the
equation
for
log[salt]
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What should you always check when working with equations?
Always check the
units
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What are the key points for plotting graphs?
Enable
data point
plotting
Ensure graph fits well
Label all axes with
units
Draw a
smooth line
through points
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Why is it important to plot graphs?
To visualize
trends
in data sets
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What is the UV max for ibuprofen?
221 nm
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How do you estimate the concentration of ibuprofen in solution X?
Using the
calibration curve
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What are the methods for predictive graphing?
Interpolation
Extrapolation
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What is interpolation in graphing?
Joining points with a
smooth
line
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What is extrapolation in graphing?
Extending
the
trend beyond known data
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What type of equations give straight line graphs?
Equations in the format y =
mx + C
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What is the general form of a parabola equation?
y =
kx<sup>2</sup>
+ C
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What is the general form of a hyperbola equation?
y =
k/x
+
C
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What is log linearization?
Converts
equations
to linear form
Facilitates easier data manipulation
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What is the gradient in log linearization?
It represents the
power
of x
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What is the intercept in log linearization?
It represents the log of the
constant
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What are the characteristics of straight line graphs?
Slope (m)
indicates
gradient
Intercept (C)
indicates
y-value
at x=0
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What is the equation of a straight line?
y =
mx
+
C
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What is the significance of the slope in a straight line graph?
It indicates the
rate of change
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What does the intercept represent in a straight line graph?
The value of y when
x = 0
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What are the key points for obtaining straight line graphs?
Ensure data points are plotted
Draw the best-fit line
Calculate the
gradient
and
intercept
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What is the purpose of plotting data sets?
To determine the
rate constant
of
degradation
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