AR of murder - a reasonable creature in being (brain dead) case example: R v Malcherek
2 seperate appeals were heard: In Malcherek, D stabbed his wife.
In both cases, V was taken to hospital and placed on life support machines
the doctors in the respective cases later turned off the life support machines, V's weren't showing any brain stem activity
D's argued that the doctor's actions constituted a novus actus interveniens which broke the chain of causation
convictions were upheld, the test of death is where the brain stem has died so V's were already dead before the machines turned off