result of interaction between bio (diathesis) + environmental (stress) influences
both vulnerability + stress are needed to develop disorder
diathesis-stress:
diathesis = evidence for role of genetics but concordance rates arent 100%
stress = stressfullife events can trigger condition e,g sexual/physical abuse
meehl's model:
original diathesisstress model - diathesis entirely genetic, one schizogene, led to development of schizotypic personality
if person lacks schizogene no amount of stress can trigger condition
in carriers of gene, chronic stress through childhood specifically schizophrenogenic mother can cause development
modern understanding:
many genes create genetic vulnerability e.g ripke108
modern view = range of factors including psychological trauma can become diathesis
readet al - early trauma alters developing brain e.g child abuse - HPA system can be overactive, making it vulnerable to later stress
modern understanding of stress:
stress can be seen psychological in nature but also includes anything that can trigger disorder (houston et al)
cannabis = stressor, increases risk of schizo up to 7x as it interferes with dopamine system, most dont develop just after smoking so must also be other factors
treatment:
combining antipsychotics + cbt, unusual to treat with cbt alone
britain = standard practice to treat with combination, US = conflict between biological + psychological models led to slower adaptation of interactionist approach
EVALUATION: original diathesis stress model is oversimplified
multiple genes cause vulnerability no single schizogene, stress comes in different forms not solely family dysfunction
vulnerability can be result of early trauma not genes, houston et al - sexual trauma vulnerability, weed trigger
theory is reductionist, issue rectified in newer models
EVALUATION: support for effectiveness of combination treatments
tarrier et al -randomly allocated315 patients to med + cbt, med + supportive counselling + control group (meds only)
2 combo groups showed lower symptom levels + no difference in rates of hospital readmission
clear practical advantage to adopting interactionist approach
EVALUATION: dont know how diathesis stress works
strong evidence to suggest underlying vulnerability coupled with stress can cause schizophrenia - unclear how it results in disorder
mechanisms by which symptoms appear + how stress + vulnerability produce them is not understood
diathesis stress is too vague + cant provide a complete account of approach