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Paper 1
Health + Disease
Defence against disease
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Created by
Mee Chan
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Cards (13)
What are the 2 lines of defence
First line of defence
-> prevents
pathogens
entering the body + non-specific
Second line of defence
= protects body from pathogens that have entered body
What does the first line of defence include
Both
physical
+
chemical
barriers
Give some examples of the physical barriers from the 1st line of defence
Skin
= prevents
pathogens
from entering +
scabs
form on cuts to prevent infections
Nose = hair + mucus traps pathogens
Trachea
= produce mucus -> traps pathogens +
cilia
waft mucus up to throat to be swallowed into the stomach
Give some examples of the chemical barriers from the 1st line of defence
Stomach acid
= kills
pathogens
Lysosomes =
lysosomes
found in tears + other bodily fluids ->
enzymes
that destroy
bacterial
cells by breaking down
cell wall
What fights the pathogens if they get past the 2nd line of defence
The
immune system
What blood cells are in the immune system
White blood cells
What are the 2 types of white blood cells
Phagocytes
Lymphocytes
What do phagocytes do
Surround
pathogens
+ engulf them
Enzymes
found in the phagocytes -> break down pathogen to destroy it
What is the process of engulfing + breaking down pathogens
Phagocytosis
Are
phagocytes
specific
or
non-specific
Non-specific
What do lymphocytes do
Pathogens enters the body with antigens on its surface
Antigens detected by lymphocytes + triggers immune response
Lymphocytes produces antibodies which bind to
antigens
so it sticks together
Easier for
phagocytes
to engulf them + destroy pathogens
Memory lymphocytes
also produced
So if body infected again -> can make antibodies quicker
What is the 1st + 2nd time when your immune system responds, called
1ST =
PRIMARY
response
2ND =
SECONDARY
response
Why does the number of antibodies in the blood increase slowly during the primary infection
As there aren't many
lymphocytes
that can make the correct antibody for the
pathogen