Intro to sterilisation processes

• What is the typical temperature range for reniranon processes?

  235°C
• What does WCACAL stand for in the context of probabilities?

  It refers to a system of utility assurance.
• What does PMU stand for?

  Non-sterile unit.
• What is the significance of the absence of bacteria in a product before its expiration?

  It ensures the product remains safe for consumption.
• What are the main procedures for sterilization mentioned?

  • Flaming
  • Chemical oxidation
  • Not practical for all products
• What is a limitation of using certain methods for sterilization?

  They may not remove endocrine disruptors.
• What is the typical temperature for most heat sterilization?

  121-124°C.
• What is the purpose of using heat sterilization?

  To eliminate microorganisms from equipment and containers.
• What is the typical temperature range for dry heat sterilization?

  160-180°C.
• How does dry heat sterilization compare to moist heat sterilization?

  It is less effective than moist heat sterilization.
• What types of radiation are used for sterilization?

  Gamma rays, x-rays, or UV light.
• Why is radiation used for heat-sensitive products?

  It sterilizes without applying heat.
• What are the gaseous agents mentioned for sterilization?

  Ethylene oxide and formaldehyde.
• How effective is gaseous sterilization compared to heat sterilization?

  It is not as effective as heat sterilization.
• What is the typical filter size for autoclaving?

  0.2-0.22 mm.
• What is the purpose of using heat in sterilization?

  To eliminate microorganisms from products.
• What are the key parameters in sterilization processes?

  • K = inactivation rate constant
  • IF = inactivation factor
  • Fo = equivalent time of moist sterilization at 121°C
  • PNSU = probability of a non-sterile unit
  • SAL = sterility assurance level