Sedation effect - histamine receptors affected, calms anxious patients
Dopamine antagonists e.g. Chlorpromazine have been around since the 1950s
Reduce action of dopamine - strongly associated with the dopamine hypothesis
Block dopamine receptors in synapse, initially dopamine levels increase after taking Chlorpromazine, then production is reduced
Normalises neurotransmission, reducing symptoms like hallucinations
