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PY 4050
Kingston Uni Lectures
Bp Homeostasis
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Cards (23)
What is blood pressure?
The pressure blood exerts on
arterial
walls
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What is the formula for blood pressure?
BP
=
CO
x
TPR
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How is cardiac output calculated?
CO =
SV
x
HR
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What does TPR stand for in blood pressure regulation?
Total Peripheral Resistance
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What is systolic blood pressure?
Peak pressure during
cardiac contraction
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What is diastolic blood pressure?
Minimum pressure when the heart is relaxed
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What are the normal ranges for systolic and diastolic blood pressure?
90-120
mmHg
and
60-80
mmHg
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What are the components of blood pressure regulation?
Long-Term Renal/Hormonal Regulation
Short-Term Neural Control
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What system determines long-term blood pressure regulation?
The
renin-angiotensin-aldosterone
system
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How is short-term blood pressure control achieved?
Through
cardiovascular
centers and
baroreceptor
stimulation
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What do baroreceptors respond to?
The
pressure
caused by the presence of blood
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What happens if blood pressure drops suddenly?
Two problems confront the
pressure control system
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What is the first problem the pressure control system faces when blood pressure drops?
To return
arterial
pressure to a survivable level
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What is the second problem the pressure control system faces after a drop in blood pressure?
To return
blood volume
to its normal level
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What are the components of the baroreceptor reflex?
Cardioaccelerator
center
Cardioinhibitor
center
Vasomotor
center
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Where are baroreceptors located?
In the
medulla oblongata
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What does the cardioaccelerator center do?
Stimulates cardiac function via
sympathetic
stimulation
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What is the role of the cardioinhibitor center?
Slows cardiac function via
parasympathetic
stimulation
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What does the vasomotor center control?
Vessel tone
and contraction of
smooth muscle
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How do changes in vessel diameter affect blood pressure?
They affect
peripheral resistance
, pressure, and flow
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What happens when mean arterial pressure (MAP) increases?
Baroreceptors
fire more often
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What happens when mean arterial pressure (MAP) decreases?
Baroreceptors
fire less often
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What is the process of how baroreceptors work?
Stretch on
carotid sinus
baroreceptors
Firing rate of carotid sinus nerve increases/decreases
Parasympathetic
/sympathetic activity adjusts
Heart rate and contractility change
Total peripheral resistance
adjusts
Arterial pressure restored to normal
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