-Serum albumin from species A is injected into species B-Species B produces antibodies specific to all the antigen sites on the albumin from species A-Serum is extracted from species B (contains antibodies specific to the antigens on the albumin from species A)-Serum from species B is mixed with serum from the blood of a third species C-The antibodies respond to their corresponding antigens on the albumin in the serum from species C-The response in the formation of a precipitate)-The greater the number of similar antigens, the more precipitate is formed and the more closely the species is related-The fewer the number of similar antigens, the less precipitate is formed and the more distantly the species are related