recreational drug effects

• What effect does cocaine have on neurotransmitters?

  It blocks their reabsorption
• What happens to neurotransmitters when cocaine is used?

  They remain in the synaptic gap
• How does cocaine affect dopamine levels in the brain?

  It increases dopamine levels in the synapse
• What is the consequence of high dopamine levels in the reward pathways?

  The body thinks there isn't enough dopamine
• What is downregulation in the context of cocaine use?

  Reduction of natural dopamine production
• What motivates a person to take more cocaine after repeated use?

  Dependency due to downregulation
• What is tolerance in relation to cocaine use?

  A higher dose is needed for the same effect
• Why does tolerance occur with repeated cocaine use?

  Due to greater downregulation of dopamine
• What happens during withdrawal from cocaine?

  There is a lack of dopamine in the brain
• What do users need to prevent unpleasant feelings during withdrawal?

  More cocaine to increase dopamine
• What are the effects of cocaine on the brain's reward pathways?

  • Blocks reabsorption of neurotransmitters
  • Increases dopamine levels in the synapse
  • Leads to downregulation of dopamine production
  • Causes dependency, tolerance, and withdrawal
• What are the key for definitions You need to know in relation to recreational drugs?

  • D down regulation
  • Dependency
  • Tolerance
  • Withdrawal