Mycoplasma: Characteristics and Diseases

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Titi pipi

Cards (57)

What property allows Mycoplasma to change shape?
Pleomorphic nature due to no cell wall
What type of anaerobes are most Mycoplasma?
Facultative anaerobes
What is unique about the cell membrane of Mycoplasma?
It contains sterols and requires cholesterol
What is a limitation of the immunofluorescence method?
Requires skilled technician
What effect does Mycoplasma pneumoniae have on host cell catalase?
It inhibits host cell catalase activity
What is a limitation of the PCR method?
Cannot distinguish live from dead bacteria
What does the morphology of Mycoplasma colonies help identify?
It helps in identifying Mycoplasma under microscopic examination
What does PCR detect to identify Mycoplasma pneumoniae?
DNA
What term describes the shape-changing ability of Mycoplasma?
Pleomorphic
What are the methods used to diagnose Mycoplasma pneumoniae infections?
Culture
PCR
Immunofluorescence
ELISA
What infection does Ureaplasma urealyticum cause?
Non-gonococcal urethritis
Which specific Mycoplasma infections are mentioned in the treatment options?
Mycoplasma pneumoniae and Ureaplasma
What diagnostic methods are more commonly used for Mycoplasma pneumoniae due to culture challenges?
PCR
Serology tests (ELISA)
What harmful substances does Mycoplasma pneumoniae produce during metabolism?
Hydrogen peroxide and superoxide
What type of agar do Mycoplasma colonies grow on?
PPLO agar
What symptoms are associated with Mycoplasma pneumoniae infection?
Persistent cough
How does the structure of Mycoplasma contribute to its antibiotic sensitivity?
The lack of a cell wall makes them sensitive to tetracyclines
What shapes do Mycoplasma colonies form on PPLO agar?
Fried-egg or mulberry shaped colonies
How long does it take for Mycoplasma colonies to develop on PPLO agar?
Up to three weeks
How do hydrogen peroxide and superoxide affect the host during Mycoplasma pneumoniae infection?
They damage host lipids and tissues
What are Mycoplasma?
Smallest free-living organisms
What infections can M. hominis cause?
Pyelonephritis, pelvic inflammatory disease, postpartum fever
How long does it take for the culture method to grow Mycoplasma pneumoniae?
Up to 3 weeks
Which class of antimicrobial agents are Mycoplasma particularly resistant to?
Beta-lactams like penicillins
How do Mycoplasma differ from bacteria?
They do not have a cell wall
Which Mycoplasma species does not follow the facultative anaerobe classification?
pneumoniae
How does the lack of a cell wall in Mycoplasma pneumoniae distinguish it from other bacteria?
It makes it resistant to beta-lactam antibiotics
What is the purpose of using PPLO agar in the culture method?
To grow Mycoplasma pneumoniae
Why do Mycoplasma have resistance to many antimicrobial agents?
They lack a cell wall
How does the lack of a cell wall in Mycoplasma affect antibiotic treatment options?
It makes penicillins and cephalosporins ineffective
What are the characteristics of Mycoplasma colonies on PPLO agar?
Grow slowly on PPLO agar
Form fried-egg or mulberry shapes
Take up to three weeks to develop
Raised in the center with smooth edges
Resemble a cooked egg or small balls
Which class of antibiotics is necessary for treating Mycoplasma pneumoniae infections?
Tetracyclines
What is required for the stability of Mycoplasma's membrane?
Cholesterol
Why is culture challenging for Mycoplasma pneumoniae?
They lack a cell wall and grow slowly
What is the role of immunofluorescence in diagnosing Mycoplasma pneumoniae?
To visualize bacteria in samples
What is the consequence of inhibiting host cell catalase in Mycoplasma pneumoniae infection?
Increased peroxide concentrations in the host
How are the edges of Mycoplasma colonies described?
They have smooth edges
Which antibiotics are Mycoplasma resistant to?
Penicillin and cephalosporins
What type of membrane do Mycoplasma have?
Sterol-containing membrane
Which antibiotic are Mycoplasma sensitive to?
Tetracyclines