support for the learning approach from animal studies. substantial body of research with non-human animals confirming the role of operant conditioning in nicotine addiction. study by Levin et al. (2010) rats could lick two water spouts. Licking one of them triggered dose of nicotine, but licking other led to no reward. rats licked the nicotine-linked waterspout more often. number of licks increased substantially over 24 sessions. suggests that effects of nicotine positively reinforce self-administration in rats, implying there is a similar mechanism in humans.