the link reaction and krebs cycle

• pyruvate producerd during glycolysis is transported across the outer and inner mitochondrial membranes via a specific pyruvate hydrogen ion symport. this is a transport protein that transports two ions or molecules in the same direction into the matrix, then:

  Pyruvate is converted to a 2 carbon acetyl group during the link reaction.

  The acetyl group is oxidised during the krebs cycle.
• where in the mitochondria does the link reaction occur?

  Matrix
• What is the first step of the link reaction?

  The carboxyl group is removed and is the origin of some of the carbon dioxide produced during respiration.
• What is the second step of the link reaction?

  The decarboxylation of pyruvate together with dehydrogenation produces an acetyl group.
• What is the third step to the link reaction?

  The acetyl group combines with co enzyme A to become acetyl co enzyme A
• What is the fourth step to the link reaction ?

  NAD is reduced
• Is ATP produced in the link reaction?

  NO.
• where in the mitochondria does the krebs cycle take place?

  Matrix
• the krebs cycle is a series of enzyme-catalyzed reactions that oxidise the acetate from the link reaction into two molecules of carbon dioxide while conserving energy by reducing the coenzymes NAD and FAD
• The reduced NAD and FAD from the Kreb's cycle will carry hydrogen atoms to the electron transport chain on the cristae where they will be involved in the produced of many ATP molecules.