ofc

• The orbitofrontal cortex, located in the frontal lobe, is responsible for processing information about potential threats, evaluating risks, and decision-making.
• In OCD, this region is often hyperactive, causing an exaggerated response to perceived danger. This heightened activity can lead to an overestimation of threats and an inability to filter out irrelevant concerns, contributing to obsessions.
• The orbitofrontal cortex is closely connected to the basal ganglia, and dysfunction in this circuit can further perpetuate OCD symptoms.​