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Antimicrobial Pharmacotherapy
Folic Acid Antagonists
Cotrimoxazole
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Mary-Anne Alfa
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Trimethoprim is mainly used in combination with
sulfamethoxazole
(TMP/SMX), and this combo is
bacteriocidal.
Cotrimoxazole is used to treat
traveler's diarrhea
and UTIs, but it’s also effective in treating haemophilus influenzae and
moraxella catarrhalis.
Cotrimoxazole is the
first-line
therapy for the treatment and prevention of
pneumocystis jirovecii
infections.
Cotrimoxazole is effective against
MRSA.
The combination of trimethoprim with sulfamethoxazole, called
cotrimoxazole.