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Med. Parasitology Class Final
Trypanosomes
Salivaria (Anterior)
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Shiva Parviz
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Cards (12)
T. Brucei gambinese?
West
africa, causes
Gambian
trypanosomiasis
Chronic
sleeping
sickness
T. brucei rhodesinse?
Found in
east
Africa, causes
Rhodesian
trypaosomiasis
Acute
sleeping
sickness
What happens to trypanosomes in the fly? (1)
Trypomastigotes are ingested in a
blood
meal then are reproduced in the
mid
gut
What happens to trypanosomes in the fly? (2)
They move to the
salivary
gland to reproduce and become
epimastigotes
What happens to trypanosomes in the fly? (3)
Epimastigotes become metacystic trypomastigotes and are then injected into the vert
What happens to trypanosomes in the 'vert? (4)
They live in the
blood
stream as
trypomastigotes
and
divide
What happens to trypanosomes in the fly?
The invade the
CNS
and cause
chronic
infection
What is the pathology?
Occurs
rarely
in the
brain
, causes
lymph
imflammation
Death occurs in a
few
months
T. b. gambinese occurs in the
brain
What happens to the trypanosome?
antigen
variations (
VSG
)
How is it diagnosed?
Finding the
parasite
within the
lood
How are trypanosomes controlled?
Through
vectors
and
reservoir
hosts