Stercoraria (Posterior)

Created by

Shiva Parviz

Cards (18)

Trypaonsoma cruzi?
Distributed in south and central America
Found in wild animals
What are the reservoir hosts?
domestic animals
What is the T. cruzi morphology?
Kinetoplast is large, dies in the form of a ?
Amastigote stage is in the muscle
What are T. cruzi's vector?
Kissing bugs, transmitted through a blood meal
What happens to T. cruzi in the reduviidae? (1)
Trypomastigotes are ingested in a blood meal and move to the hind gut
What happens to T. cruzi in the reduviidae? (2)
Become epimastigotes and reproduce, which then appear in the rectum as metacytic trypomastigotes
What happens to T. cruzi in the reduviidae? (3)
Are dropped into the hosts skin as a shit ball, infected when rubbed into the wound
What happens to T. cruzi in the 'vert? (1)
Trypomastigotes cause acute inflammation and move to the lymph nodes
What happens to T. cruzi in the 'vert?
Become amastigotes in the monocyte, divide and form pseudocysts then transform back into trypomas.
What happens to T. cruzi in the 'vert? (3)
Forms a psuedocyst, the trypomastigotes can infect any cell in the body
What happens to T. cruzi in the 'vert? (4)
Become amastigotes to start the process all over again
What is this acute phase?
Most common and is severe in children, causes Chagas
What is this acute phase?
Psuedocysts can be found in nearly every type of cell
Anemia, nerve damage, chills, muscle and bone damage
Death occurs in 3 to 4 weeks
What is the chronic phase?
Nervous system disfunction
Can go asymptomatic for years, 80% of cardiac nerve ganglia are lost
What is the chronic phase?
Autonomic ganglia in the esophagous and the colon are also destroyed
What is the chronic phase?
Megacolon and megaesophagous occur due to the destruction of nerve ganglia
What is the diagnosis for T. cruzi?
Trypomastigotes in blood or the lymph system
Inoculated into sterile rodents and tissue smears are preformed
What is T. cruzi weak to?
Chemotherapy