→ BZs bind to a specific site on the GABA- A receptor. This changes the shape of the receptor, making it more responsive to GABA.
As a result, GABA binds more easily and has a stronger inhibitory effect. When GABA binds to its receptor (with the help of BZs), chloride ion (Cl ̄) channels open wider.
More chloride ions enter the neuron, making it even less likely to fire.
More chloride ions enter the neuron, making it even less likely to fire.
